Inflammation and COVID-19

Stay Away From Anything That Causes Inflammation

Medical experts are conveying to avoid anything that causes inflammation during this coronavirus pandemic, but some people have genes that make them more likely to experience inflammation. In 2019, scientists discovered that the coronavirus can trigger an inflammatory response making the symptoms and illness more severe .

From mild stress to chronic health conditions, inflammation can and will wreak havoc on your body and mind. Inflammation is caused by a complex mix of genetic and environmental factors, which can make it very difficult to address – especially while you’re suffering from exhaustion, depression, or any other inflammation-related symptoms.

Excessive immune response related to COVID-19

Every week, more is being learned about the incredible physiological harm that the coronavirus is capable of doing to those infected. This is the critical reason why this virus should not be taken likely.

Some clinicians suspect the driving force in many gravely ill patients’ downhill trajectories is a disastrous overreaction of the immune system known as a “cytokine storm.” Cytokine storm is a hyperinflammatory condition caused by an overactive immune system. According to scientific research, a cytokine storm is a driving force in COVID-19 mortality rates.

Cytokines are chemical signaling molecules that guide a healthy immune response; but in a cytokine storm, levels of certain cytokines soar far beyond what’s needed, and immune cells start to attack healthy tissues. Blood vessels leak, blood pressure drops, clots form, and catastrophic organ failure can ensue. This can cause inflammation and damage to the lungs and other organs.

Cytokine storm, a life-threatening disorder involving cytokine elevations and immune-cell hyperactivation, has various causes and is characterized by constitutional symptoms, systemic inflammation, and multiorgan dysfunction. Selective interventions can ameliorate the illness.

— NEJM (@NEJM) December 4, 2020

Corticosteroids

Doctors have used a class of medicines called corticosteroids – including one called dexamethasone – to help tame that response. These are medications that have been around for a long time and are readily available. “We know this medication very well. It’s been used for many other purposes, and we know the side effects profile and what it can do to the body,” pulmonary and critical care physician Lokesh Venkateshaiah, MD says.

Its use to treat COVID-19 stems from the success of the RECOVERY trial carried out by researchers in the United Kingdom. In the study, hospitalized patients with COVID-19 who received dexamethasone for up to 10 days were less likely to die than those who didn’t. That benefit was only seen in very sick patients – those who had oxygen levels less than 93% or needed supplemental oxygen.

But, doctors have to be careful with dosing. “Overdoing it with this drug can potentially put patients at risk for new infections, especially bacterial infections, or even fungal infections,” Dr. Venkateshaiah cautions.

Experts across the world are studying whether different medications can help people fight COVID-19. Here’s a look at four that have been getting attention recently. https://t.co/94tmmLGyaE

— Cleveland Clinic (@ClevelandClinic) December 7, 2020

COVID-19 fatigue

Yet after more than ten months, Americans are getting COVID-19 fatigue. Much of the current rise in COVID-19 infections is due to community spread. Taking precautions to prevent the spread of COVID-19 is critical, particularly as the virus continues to evolve.

Your best defense to avoid serious illness and against the physiological harm caused by COVID-19 is to remain vigilant. You must continue to wear a mask, maintain physical distancing and disinfect high-touch surfaces daily. Additionally, you must get vaccinated for the seasonal influenza, wash your hands regularly and stay away from others if you are feeling ill.

COVID-19 vs Seasonal Influenza

COVID-19 symptoms generally appear two to 14 days after exposure. And, with COVID-19, you may experience loss of taste or smell. COVID-19 is more contagious and spread more quickly than the seasonal flu. Severe illnesses, such as lung injury, may be more frequent with COVID-19 than with the flu. The death rate also appears to be higher with COVID-19 than the flu.

Wearing masks

Wearing a cloth mask has been shown to help decrease the spread of COVID-19. Research shows that a significant number of people who have COVID-19 do not have any symptoms and are considered asymptomatic. These people may not know they are transmitting the virus to others when they talk, sneeze or cough, or raise their voice, such as with singing or shouting.

You should wear a cloth mask to reduce the chance of transmitting respiratory droplets to others around you. You wear a mask to protect others, and they wear a mask to protect you.

References:

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