Healthy Aging: Nicotinamide Riboside

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Blog Post at a Glance

  • The trace nutrient nicotinamide riboside (NR), a precursor of nicotinamide adenine dinucleotide (NAD+) and a form of vitamin B3, may help slow brain aging
  • NR may help to boost levels of NAD+, which typically declines in the brain with age, leading to metabolic and cellular dysfunction
  • The NAD+ precursor niacinamide is also beneficial, but it’s not widely promoted because it costs much less than other NAD+ precursors, including NR
  • Since NAD+ declines with age, boosting it has been described as a fountain of youth for extended lifespan and increased resilience to disease

Nicotinamide Riboside (B3) is often celebrated as a “fountain of youth” and has been linked to many health benefits, including better endurance, improved cardiovascular health, cognitive enhancement, and anti-aging support.

Nicotinamide riboside is naturally produced in our bodies. It’s a chemical compound which acts as a precursor to vitamin B3.

For a long time, nobody really knew about nicotinamide riboside. Its mechanisms were not well-understood and, at first glance, it didn’t look like it profoundly affected the body in any way.

Over the past decade, a number of studies have been performed on nicotinamide riboside, radically changing the way scientists think and feel about this chemical compound.

Nicotinamide riboside has been linked to a number of surprising and powerful benefits. Early research on the chemical has been noteworthy.

Established scientist from Harvard and Cornell University have had much to say about this breakthrough anti-aging fighter that is making 55 year old individuals feel like they are 35 in the gym again.

That research, performed by Dr. David Sinclair of Harvard Medical School, showed that each mouse’s cell age decreased from 2 years to 6 months after being given molecules of Nicotinamide Riboside. In other words, mice that were 2 years old had the cells of 6 month old mice after being administered Nicotinamide Riboside.

So not only does Nicotinamide Riboside reduce the effects of aging, it actually appears to turn back time and make the cells function like they did when they were younger.

One recent nicotinamide riboside study concluded that taking nicotinamide riboside as an oral supplement, “resulted in a remarkable induction of mitochondrial biogenesis and oxidative metabolism, with an increase in mitochondrial mass.”

Mitochondria is directly linked to aging. As our bodies age, our mitochondrial production – and functionality – declines. This leads to a wide range of degenerative diseases and ultimately makes us look and feel older.

By promoting mitochondrial biogenesis, nicotinamide riboside may be able to “kickstart” the body’s anti-aging processes in a way that no other chemical compound can. That means you look, feel, and think younger.

Nicotinamide Riboside (NR) acts as a highly effective NAD+ booster, but it also works as a vitamin B3 (niacin) supplement.

Nicotinamide adenine dinucleotide (NAD+) is a key coenzyme found in all living cells. It is a dinucleotide, which means that it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base, and the other contains nicotinamide.

NAD+ is essential for life, one of the most versatile molecules in the body, and an important area of focus for aging research.

Since NAD+ declines with age, boosting it has been described as a fountain of youth for extended lifespan and increased resilience to disease.

In 2020, James Clement, author of “The Switch: Ignite Your Metabolism With Intermittent Fasting, Protein Cycling, and Keto,” said NAD+ may be depleted by 50% by the time you’re 60 (compared to in your 20s or 30s), and when you’re 70 you may only have 10% of the amount you did when you were younger.

“And then at 80, there’s almost none,” he said, adding that this will seriously impair your body’s ability to repair broken DNA. “You can see how this huge build-up of damaged DNA in every cell of your body is potentially one of the driving forces of these morbidities that you see with aging, heart disease, cancer [and] Alzheimer’s …“

Nicotinamide riboside is one of the most effective NAD+ precursors to support nucleus and mitochondrial health. That means it boosts cellular energy and reduces the effects of aging by enhancing cellular communication throughout the body and mind.

References:

  1. https://supplementpolice.com/niagen/
  2. https://supplementpolice.com/nicotinamide-riboside/
  3. https://drjosephmercola.com/could-this-vitamin-slow-brain-aging-and-ward-off-alzheimers/
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