COVID-19, One Year Later. Here’s What We’ve Learned.

“The vaccines are our best hope to contain the virus; and while the CDC’s guidance may change based on new evidence, you should follow their current guidance: Keep wearing your mask, practice social distancing and wash your hands.”  Dr. Andrea Klemes

By Dr. Andrea Klemes, MDVIP’s Chief Medical Officer

It was March 11 last year when the World Health Organization first announced that the coronavirus had reached pandemic stage. At the time, there were 118,000 cases in 114 countries. A year later and there are more than 114 million cases and 2.5 million deaths worldwide.

In the year since the pandemic officially started, doctors, researchers and the American public have learned a lot about the virus. We know how it spreads — through droplets and in the air; we know how it likely doesn’t spread — on surfaces (you should still wash your hands regularly); we know the virus isn’t seasonal like flu – it didn’t go away during the summer; and we know that we can fight it, both through prevention and treatment.

Speaking of treatment, we’ve learned a lot about what works in the fight against COVID-19, the condition caused by the coronavirus. The anti-inflammatory steroid drug dexamethasone, for example, works in many patients on supplemental oxygen or ventilators. Antibodies — either from convalescent plasma or man-made ones from monoclonal antibody treatments — seem to keep some patients from more severe illness. These treatments have been granted emergency use authorization by the Food and Drug Administration.

Even simple things, like turning patients prone (lying face down) have turned out to be lifesaving for many people hospitalized with the disease.

But there’s still much we don’t know. And there’s still a lot of misinformation and myths swirling around 12 months after the pandemic began. I thought it would be helpful to recap some key learnings.

Vaccines are here, but the virus isn’t going away any time soon.

See the source image
It’s hard to believe that in a little less than a year scientists created numerous vaccines to combat the coronavirus. In fact, the Food and Drug Administration approved a third vaccine last week — and this one, from Johnson & Johnson, is a single-dose vaccine that’s easier to transport and store. It should help vaccines become more widely available in the next couple of months.

If you’ve already gotten your vaccine, your behavior shouldn’t change — that’s the advice of the Centers for Disease Control and Prevention. That’s because the vaccines prevent severe illness from infection. You may still be able to get the virus and spread it.

This advice may change. Promising but unpublished studies suggest that vaccinated individuals carry lower viral loads and may be at lower risk to spread the virus. If you’re thinking, why get the vaccine if I still have to wear a mask? Get the vaccine when it’s your turn. The vaccines are our best hope to contain the virus; and while the CDC’s guidance may change based on new evidence, you should follow their current guidance: Keep wearing your mask, practice social distancing and wash your hands.

One rule that has changed for those who have been vaccinated: You may not have to quarantine after exposure if you meet certain criteria and it’s been more than two weeks since your last dose.

Eating at a restaurant increases your risk of getting the virus.
We love eating at restaurants, but many are poorly ventilated and crowded with people. Even at reduced capacity, the CDC rates eating inside at a restaurant to be higher risk than other activities. A study from six months ago suggested that COVID-19 positive patients were twice as likely as those who tested negative to have eaten at a restaurant in the two weeks leading up to their illness.

It’s possible that people who eat at restaurants during the pandemic take other risks that increase their chances of getting the virus, but there are also early studies that track breakouts to restaurant eaters.

It’s still safer to get your food to go — or eat outside away from other diners.

So does gathering with your family.
Just like eating out, there are plenty of studies showing the transmission of the virus when families get together. Among adults with COVID-19, 42 percent reported close contact with a person with COVID-19 — and most of those close contacts were with family members.

In one case study from last summer, a single COVID-positive adolescent on a family vacation with three different families spread the illness to 11 other family members. There are dozens of cluster studies like these from contact tracing efforts — weddings, reunions, holiday parties, barbecues and even more intimate gatherings. Getting together with family without proper protocols can result in spreading events.

Even without gatherings, household members are often the point of contact for new COVID cases. Household transmission of this coronavirus is 16.6 percent higher than with past pandemics like SARS and MERS.

To be fair, more infections have been traced to other kinds of activities than seeing family — from workplaces to prisons to assisted living facilities to colleges. But you shouldn’t let your guard down when you’re around your family.

Six feet of distance probably isn’t enough.
Early guidance from the CDC defined close contact as spending 15 minutes or more within six feet of a person infected with COVID-19. The six-foot distance was based on COVID transmission from droplets, which we emit when we talk, sneeze or cough. We’ve been studying viral transmission by droplets since the 1890s.

Of course, there are plenty of studies over the years that suggest droplets can travel further. The problem with COVID is that you can become infected from aerosol transmission — smaller droplets and particles can float in the air for minutes and hours and travel far from the source. Still, the CDC says that most transmission comes from close contact with infected individuals.

As for time, that one’s trickier. Some school systems and employers liberally interpreted the 15 minutes to mean that as long as you kept contact brief, you were okay. But repeated exposure can also result in an infection, which is one reason the CDC changed the guidance last fall to 15 minutes over a 24-hour period. Here’s the bottom line: The more you interact with others and the longer that interaction lasts, the greater your chance of contracting COVID.

The best way to prevent spread is to avoid unnecessary exposure.

Yes, masks help prevent the spread of the virus.
I know a lot of people have had a hard time warming up to face masks. Early in the pandemic, public health officials lacked clear evidence about the effectiveness of masks and hesitated to recommend them. But 12 months later, there’s a raft of evidence that masks (double ply cloth, surgical and N95) reduce the transmission of the coronavirus. In fact, the Proceedings of the National Academy of Sciences of the U.S., which recently published a review of studies about masks and COVID-19 transmission, concluded:

“The preponderance of evidence indicates that mask wearing reduces transmissibility per contact by reducing transmission of infected respiratory particles in both laboratory and clinical contexts.”

Some study highlights:

Masks were 79 percent effective at preventing household transmission, if used by all members of the household before symptoms showed.

The devil is in the details. We know from COVID studies and previous viral studies that masks reduce risk of transmission for the wearer and for the people around them if the wearer is sick.

Double masks may even be better.
One mask works if you wear it correctly. Two might actually be better.

The CDC recently released new masking guidelines based on studies it did to determine how to improve their efficacy. The agency looked at wearing a cloth mask over a medical procedure mask (often called a surgical mask, but not an N95) and whether knotting the ear loops of a medical procedure mask and then tucking in and flattening the extra material close to the face would reduce risk.

Both modifications improved the masks effectiveness. According to the CDC’s experiments, an unknotted medical procedure mask blocked 42 percent of the particles from a simulated cough. A cloth mask blocked 44.3 percent. Knotting the surgical mask alone blocked 63 percent of particles. When the cloth mask was combined with the knotted surgical mask, it blocked 92.5 percent of particles.

The CDC has since updated its recommendations. If you use an N95 or KN95 mask, the agency does not recommend double masking. It also doesn’t recommend doubling up surgical masks.

Testing negative doesn’t mean you stay negative.
This may be one of the hardest things for people to understand. A lot of people get tested after they’re exposed, but you can test negative one day and positive the next, depending on the time from when you were exposed, the course of the infection and the type of test you took.

When you’re exposed to someone with the virus and become infected, symptoms may show a few days after exposure or up to two weeks later. If you test too soon, a test may not pick up the infection. If you’re asymptomatic, a rapid antigen test may not pick up your infection at all. Accuracy is lower in antigen tests than PCR tests, especially in those who aren’t showing symptoms.

That’s why it’s so important to observe CDC guidelines when it comes to testing and exposure. If you’ve been exposed to the virus, the CDC recommends you quarantine for 10 days, provided you remain asymptomatic. You can reduce this time to seven days if you show no symptoms and do not test positive for the virus on day 5 or later.

The new variants are a reason to be vigilant.
The new variants are more than troublesome. Many of them are more communicable and one, the British variant, is looking like it may be more virulent. This is why we need to keep washing our hands, wearing masks and practicing social distancing. And why we should get the vaccine when it’s our turn. Don’t let up now!

With a little extra effort from all of us, I believe we can beat back this virus, and we’re well on the way. We’re better at treating it, and we know how to stop its spread. If enough of us do these things, there’s a chance these variants won’t make the impact that some researchers currently fear.

We may have to take booster shots in the future, but that’s a lot better than where we were a year ago when we had no vaccine, few promising treatments and knew very little about COVID-19.

What a difference a year makes.


Reference:

  1. https://www.mdvip.com/about-mdvip/blog/what-you-need-know-about-coronavirus-or-covid-19

COVID-19 Cases Have Dropped 77% in Six Weeks

“COVID cases have dropped 77% in six weeks. Experts should level with the public about the good news.”  Dr. Marty Makary, surgeon and professor at the Johns Hopkins School of Medicine and Bloomberg School of Public Health

Dr. Anthony Fauci, White House COVID adviser, reassured Americans that the millions of coronavirus vaccine doses delayed by winter storms in the Northeast and Texas would be delivered this week as the nation approaches the half million mark for deaths due to Covid-19.

Despite the delays in vaccine delivery, there are signs the pandemic has eased in the U.S. in recent weeks. The 7-day average for daily deaths has fallen more than a third since mid-January, while new infections are down nearly 70% since then, according to data from the New York Times. Additionally, according to data from John Hopkins University more than 498,900 people have died of COVID-19 as of Monday morning. Globally, 2.4 million people have passed due to the virus.

Dr. Marty Makary, a surgeon and a professor at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, believes that the coronavirus will be “mostly gone” and ” normal life will return” by April 2021.  In an op-ed published by The Wall Street Journal, Dr. Makary argued that half of the U.S. has already reached herd immunity because there are more coronavirus cases in the country, possibly 6.5 times as many, than the 28 million that have been reported.

“There is reason to think the country is racing toward an extremely low level of infection,” Makary wrote. “As more people have been infected, most of whom have mild or no symptoms, there are fewer Americans left to be infected. At the current trajectory, I expect COVID will be mostly gone by April, allowing Americans to resume normal life.”

Dr. Makary cites observational data which shows that the majority of Americans may already be protected not only from COVID-19 but also its new variants.  He states, “My prediction that Covid-19 will be mostly gone by April is based on laboratory data, mathematical data, published literature and conversations with experts.”

“But the consistent and rapid decline in daily cases since Jan. 8 can be explained only by natural immunity,” Makary wrote. “Behavior didn’t suddenly improve over the holidays; Americans traveled more over Christmas than they had since March. Vaccines also don’t explain the steep decline in January. Vaccination rates were low and they take weeks to kick in.”

Even with daily new infections falling below 70,000 on a 7-day rolling average, the Centers for Disease Control and Prevention has warned that more contagious variants could cause those numbers to rise again.


References:

  1. https://www.newsweek.com/john-hopkins-doctor-thinks-covid-will-largely-gone-april-half-us-has-herd-immunity-1570615
  2. https://www.wsj.com/articles/well-have-herd-immunity-by-april-11613669731
  3. https://meaww.com/dr-marty-makary-johns-hopkins-surgeon-professor-claims-us-covid-mostly-gone-april-us-herd-immunity
  4. https://www.ftportfolios.com/common/contentfileloader.aspx?contentguid=2a5d4dcf-5eda-4310-8d23-af162f8fb7e9

Masks Protect Those Around You

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COVID-19 spreads mainly from person to person through respiratory droplets. Respiratory droplets travel into the air when you cough, sneeze, talk, shout, or sing. These droplets can then land in the mouths or noses of people who are near you or they may breathe these droplets in.

Masks are a simple barrier to help prevent your respiratory droplets from reaching others. Studies show that masks reduce the spray of droplets when worn over the nose and mouth.

woman wearing face covering, with a detail showing how the cloth barrier helps to contain respiratory droplets that she exhales

You should wear a mask, even if you do not feel sick. This is because several studies have found that people with COVID-19 who never develop symptoms (asymptomatic) and those who are not yet showing symptoms (pre-symptomatic) can still spread the virus to other people. The main function of wearing a mask is to protect those around you, in case you are infected but not showing symptoms.

It is especially important to wear a mask when you are unable to stay at least 6 feet apart from others since COVID-19 spreads mainly among people who are in close contact with one another (within about 6 feet).

Your mask offers some protection to you

A cloth mask also offers some protection to you too. How well it protects you from breathing in the virus likely depends on the fabrics used and how your mask is made (e.g. the type of fabric, the number of layers of fabric, how well the mask fits). CDC is currently studying these factors.

Who should or should not wear a mask

CDC guidance is that everyone 2 years of age and older should wear a mask in public settings and when they are around people who do not live in their household.  However, according to CDC, masks should not be worn by:

  • Children younger than 2 years old
  • Anyone who has trouble breathing
  • Anyone who is unconscious, incapacitated or otherwise unable to remove the mask without assistance
  • Wearing masks may be difficult for some people with sensory, cognitive, or behavioral issues. If they are unable to wear a mask properly or cannot tolerate a mask, they should not wear one,

https://youtu.be/dSvff0QljHQ

Key Takeaways:

  • People age 2 and older should wear masks in public settings and when around people who don’t live in their household.
  • Masks offer some protection to you and are also meant to protect those around you, in case you are unknowingly infected with the virus that causes COVID-19.
  • A mask is NOT a substitute for social distancing. Masks should still be worn in addition to staying at least 6 feet apart.
  • Wash your hands with soap and water for at least 20 seconds or use hand sanitizer with at least 60% alcohol after touching or removing your mask.
  • Postponing holiday travel & staying home is the best way to protect yourself & others from COVID19. If you decide to travel internationally, check out CDC’s testing recommendations to help make travel safer. 
  • Masks may not be necessary when you are outside by yourself away from others, or with other people who live in your household. However, some localities may have mask mandates while out in public and these mandates should always be followed.


References:

  1. https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/cloth-face-cover-guidance.html

Vaccination and Wearing Masks

“Once enough people have some immunity, either because of previous infection or because of vaccination, the virus will have a hard time spreading through the community.” Consumer Reports

Researchers hope that Americans getting vaccination will be sufficient to end the pandemic once there is sufficient supply and enough pf the population gets vaccinated.

In trying to understand the readily available vaccine information and how it will affect the lives of Americans, Consumer Reports has reviewed government guidance and consulted with public health experts to provide insight to their readers about the vaccine candidates.

Vaccination equals two doses

Vaccines require two doses—an initial shot and a booster, taken several weeks later. Generally with a two-dose vaccine, it takes about two weeks from the second dose for a vaccine’s protection to fully kick in, according to Natalie Dean, PhD, an assistant professor of biostatistics specializing in infectious disease and vaccine development at the University of Florida.

Though two doses are necessary, the FDA’s analysis of the Pfizer vaccine indicates that people appear to be somewhat less likely to get COVID-19 within two weeks of receiving the first dose.

It’s unclear how long protection from that first dose may last. And the second dose is still required for full protection, to ensure a more durable immune response. 

Halting the virus transmission

It is not known definitely whether getting vaccinated will prevent you from spreading the coronavirus to others. Thus, preventive measures such as social distancing, washing hands, and wearing a mask will remain important even after you get vaccinated, according to the CDC.

More research is required before scientists can say exactly how many people need to be vaccinated to achieve “herd immunity “. It’s possible that with extremely effective vaccines showing 95 percent efficacy, we might hit the point where communities are protected by the time somewhere between 60 and 70 percent of people have been vaccinated, according to Kathleen Neuzil, MD, a professor of vaccinology and director of the Center for Vaccine Development and Global Health at the University of Maryland in Baltimore. 

It will be possible for vaccines, as long as Americans get vaccinated, to have a significant impact on ending this pandemic.

Severe allergic reactions

In the U.K., public health regulators have advised that anyone with a history of a severe, potentially life-threatening allergic reaction to a vaccine, medicine, or food should not receive the vaccine. Two healthcare workers were reported to have had severe allergic reactions after receiving the vaccine. Public health experts worry that the reports could frighten people with allergies and make them think they should avoid getting the vaccine.

From Pfizer’s vaccine trial results, there were no severe allergic reactions. Deliberately, the trials excluded people who had previously had severe allergic reactions to vaccines, a Pfizer scientist said during the advisory panel’s discussion.

The FDA plans to advise that people who are allergic to components of the vaccine should not get it, an agency scientist explained. The FDA’s earlier review of Pfizer’s trial data found slightly more potential minor allergic reactions in the group that received the vaccine than in the placebo group, but none of these were severe, and none occurred immediately after people received their doses of vaccine.


References:

  1. https://www.consumerreports.org/vaccines/your-questions-about-a-coronavirus-vaccine-answered/?EXKEY=YSOCIAL_FB&fbclid=IwAR2LW6PC_JSykJwyG-Kv9ozQkNvxH-1VnYmAby-MJIr8kSJfHm7UwtyH3k8

mRNA Vaccine Safe and Its Side Effects

Moderna and Pfizer COVID-19 vaccine trials show that side effects are common in participants and it appears that the more significant symptoms develop following the second dose.

The Pfizer-BioNTech’s mRNA coronavirus vaccine (BNT162b2) is both safe and effective, according to the U.S. Food and Drug Administration (FDA). FDA said results from Pfizer’s large, ongoing study showed the vaccine, which was co-developed with Germany’s BioNTech, demonstrated more than 95% efficacy across people of different ages, races and underlying health conditions, including diabetes and obesity. And partial protection from coronavirus appears to begin 12 days after the first dose, according to Pfizer. Consequently, Pfizer requested and the vaccines are expected to be approved for emergency use authorization (EUA) by the FDA as early as this week.

And this week, a committee of leading U.S. vaccine scientists recommended that the Food and Drug Administration authorize the first COVID-19 vaccine for Americans.

FDA approval of a drug means that the agency will have determined, based on substantial evidence, that the drug is effective for its intended use, and that the benefits of the drug outweigh its risks when used according to the product’s approved labeling. Approval of the he vaccine will help reduce the risk of disease. The vaccine works with the body’s natural defenses to safely develop protection (immunity) to disease, according to the FDA’s website.

How an mRNA vaccine works

Messenger RNA vaccines, called mRNA for short, is a new kind of vaccine technology that has never before been licensed in the U.S. mRNA vaccines contain material from the virus that causes COVID-19 that gives our cells instructions for how to make a harmless protein that is unique to the virus. The objective of a vaccine is to teach your immune systems how to recognize and fight the virus that causes COVID-19, according to the Centers for Disease Control and Prevention.

Messenger RNA vaccines aren’t like past seasonal influenza vaccines. An mRNA vaccine is essentially just a piece of genetic code that contains instructions for our body. The mRNA tells our cells to make a protein — the same protein that is the spike on top of the actual coronavirus. This is what triggers the immune response in these types of vaccines.

In contrast, past seasonal influenza vaccine puts a weakened or inactivated virus into your body to trigger an immune response, which then produces antibodies. Those antibodies are what ultimately protects you from getting infected if you ever encounter the real virus.

It typically takes a few weeks for the body to build immunity against COVID-19 infection after vaccination. And after vaccination, the process of building immunity can cause symptoms or “side effects”. These symptoms are normal and are a sign that the body is building immunity.

Side effects

Sometimes the vaccine process of teaching your immune system how to react to the virus can cause symptoms. These symptoms are normal and are a sign that the body is building immunity. Moreover, no major safety issues were uncovered and common vaccine-related side effects like fever, fatigue and injection site pain were tolerable, according to the FDA.

The most common vaccine side effects were injection site reactions (84.1%), fatigue (62.9%), headache (55.1%), muscle pain (38.3%), chills (31.9%), joint pain (23.6%), and fever (14.2%), acc riding to the report submitted to the FDA.

Severe adverse reactions occurred in 0.0% to 4.6% of participants and appeared were more frequent after the second dose than after the first. The frequency of serious adverse events was low (<0.5%), without meaningful imbalances between study arms.

Although some COVID-19 trial participants reported COVID-like symptoms, it is impossible to contract the coronavirus from the vaccine, because the mRNA vaccines develop by Pfizer and Moderna don’t use the live virus. 

Bottomline

Getting vaccinated is one of many steps you can take to protect yourself and others from COVID-19.  Vaccines work with your immune system so your body will be ready to fight the virus if you are exposed.


References:

  1. https://www.cnbc.com/2020/12/08/pfizer-moderna-covid-vaccine-side-effects-trials.html?__source=iosappshare%7Ccom.microsoft.msedge.EMMXShareExtension
  2. https://www.fda.gov/media/144245/download
  3. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/how-they-work.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fvaccines%2Fabout-vaccines%2Fhow-they-work.html
  4. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/vaccine-benefits/facts.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fvaccines%2Fabout-vaccines%2Fvaccine-myths.html

Inflammation and COVID-19

Stay Away From Anything That Causes Inflammation

Medical experts are conveying to avoid anything that causes inflammation during this coronavirus pandemic, but some people have genes that make them more likely to experience inflammation. In 2019, scientists discovered that the coronavirus can trigger an inflammatory response making the symptoms and illness more severe .

From mild stress to chronic health conditions, inflammation can and will wreak havoc on your body and mind. Inflammation is caused by a complex mix of genetic and environmental factors, which can make it very difficult to address – especially while you’re suffering from exhaustion, depression, or any other inflammation-related symptoms.

Excessive immune response related to COVID-19

Every week, more is being learned about the incredible physiological harm that the coronavirus is capable of doing to those infected. This is the critical reason why this virus should not be taken likely.

Some clinicians suspect the driving force in many gravely ill patients’ downhill trajectories is a disastrous overreaction of the immune system known as a “cytokine storm.” Cytokine storm is a hyperinflammatory condition caused by an overactive immune system.  According to scientific research, a cytokine storm is a driving force in COVID-19 mortality rates.

Cytokines are chemical signaling molecules that guide a healthy immune response; but in a cytokine storm, levels of certain cytokines soar far beyond what’s needed, and immune cells start to attack healthy tissues. Blood vessels leak, blood pressure drops, clots form, and catastrophic organ failure can ensue. This can cause inflammation and damage to the lungs and other organs.

Corticosteroids

Doctors have used a class of medicines called corticosteroids – including one called dexamethasone – to help tame that response. These are medications that have been around for a long time and are readily available. “We know this medication very well. It’s been used for many other purposes, and we know the side effects profile and what it can do to the body,” pulmonary and critical care physician Lokesh Venkateshaiah, MD says.

Its use to treat COVID-19 stems from the success of the RECOVERY trial carried out by researchers in the United Kingdom. In the study, hospitalized patients with COVID-19 who received dexamethasone for up to 10 days were less likely to die than those who didn’t. That benefit was only seen in very sick patients – those who had oxygen levels less than 93% or needed supplemental oxygen.

But, doctors have to be careful with dosing. “Overdoing it with this drug ­can potentially put patients at risk for new infections, especially bacterial infections, or even fungal infections,” Dr. Venkateshaiah cautions.

COVID-19 fatigue

Yet after more than ten months, Americans are getting COVID-19 fatigue. Much of the current rise in COVID-19 infections is due to community spread. Taking precautions to prevent the spread of COVID-19 is critical, particularly as the virus continues to evolve.

Your best defense to avoid serious illness and against the physiological harm caused by COVID-19 is to remain vigilant. You must continue to wear a mask, maintain physical distancing and disinfect high-touch surfaces daily. Additionally, you must get vaccinated for the seasonal influenza, wash your hands regularly and stay away from others if you are feeling ill.

COVID-19 vs Seasonal Influenza

COVID-19 symptoms generally appear two to 14 days after exposure. And, with COVID-19, you may experience loss of taste or smell. COVID-19 is more contagious and spread more quickly than the seasonal flu. Severe illnesses, such as lung injury, may be more frequent with COVID-19 than with the flu. The death rate also appears to be higher with COVID-19 than the flu.

Wearing masks

Wearing a cloth mask has been shown to help decrease the spread of COVID-19. Research shows that a significant number of people who have COVID-19 do not have any symptoms and are considered asymptomatic. These people may not know they are transmitting the virus to others when they talk, sneeze or cough, or raise their voice, such as with singing or shouting.

You should wear a cloth mask to reduce the chance of transmitting respiratory droplets to others around you. You wear a mask to protect others, and they wear a mask to protect you.


References:

  1. https://get.selfdecode.com/gene-reports/nm/inflammation/?utm_source=selfhacked&amp;utm_medium=partnerad&amp;utm_campaign=inflammation_report
  2. https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-7-top-covid-19-myths/
  3. https://health.clevelandclinic.org/do-any-drugs-really-work-as-coronavirus-treatments/amp/?__twitter_impression=true

COVID-19 Vaccine Safe…Skepticism High Among Americans

Gallup polling shows about six in ten Americans are willing while four in ten Americans remain skeptical about taking a coronavirus vaccine

Polling has shown that there is lingering skepticism among Americans in taking the vaccines. Most cite the fact that the vaccine has been produced in months rather than the years it normally takes as the reason for the skepticism.

Gallup poll released November 17, 2020, found Americans’ willingness to be vaccinated against COVID-19 rebounded. Fifty-eight percent (58%) of Americans in the latest poll say they would get a COVID-19 vaccine, up from a low of 50% in September while 42% of Americans would not agree to get a vaccine approved by the Food and Drug Administration. A plurality of the latter said the rushed timeline was a concern. Others cited a need to confirm it is safe or effective. Twelve percent said they generally don’t trust vaccines.

Globally, 61% of the world strongly agree with the statement, “vaccines are safe”, according to Gallup.

Unfounded fears about vaccine safety

“The process of the speed did not compromise, at all, safety, nor did it compromise scientific integrity,” Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases, said. “It was a reflection of the extraordinary scientific advances in these types of which allowed us to do things in months that actually took years before.”

Former Presidents Barack Obama, George W. Bush and Bill Clinton have all indicated that they will publicly take the coronavirus vaccine once approved and as soon as available to them, based on the priorities determined by public health officials in an effort to promote the vaccine’s use and safety.

Public health officials face an uphill climb in convincing a good share of the American public that the vaccine is safe and to receive the vaccination.


References:

  1. https://www.11alive.com/article/news/health/coronavirus/obama-coronavirus-vaccine/507-43ebe52f-3ad5-45e1-916f-1386f6eda819?utm_campaign=snd-autopilot
  2. https://news.gallup.com/poll/325208/americans-willing-covid-vaccine.aspx

Measuring Oxygen Levels at Home

With a pulse oximeter, you can monitor your oxygen levels and have a better measure for whether you need to contact your healthcare provider.

Some COVID-19 patients have dangerously low levels of oxygen, which is being called “silent hypoxia.”

When your body doesn’t have enough oxygen, you could get hypoxemia (low oxygen in your blood) which may lead to hypoxia (low oxygen in your tissues) when your blood doesn’t carry enough oxygen to your tissues to meet your body’s needs. These are dangerous conditions. Without oxygen, your brain, liver, and other organs can be damaged just minutes after symptoms start.

Many doctors are recommending that individuals testing positive for COVID-19 monitor their oxygen levels at home with a pulse oximeter. Pulse oximeters are devices you place on your fingertip to measure the amount of oxygen in your blood. These devices use small beams of light that pass through your finger to measure how much oxygen your blood is carrying and your pulse.

Normal oxygen level

A normal oxygen level measured by a pulse oximeter is around 97%. Medical experts start to worry oxygen level drops under 90% because this can affect the amount of oxygen going to your brain and other vital organs. Levels below 80% are considered dangerous and increase the risk of organ damage.

Usually, people with low oxygen levels appear uncomfortable, sometimes even to the point of appearing to be gasping for air. Although, doctors do not clearly understand why some COVID-19 patients have such low levels of oxygen without appearing uncomfortable.

Doctors are divided on whether home monitoring of oxygen levels with a pulse oximeter. In an opinion piece for The New York Times, one ER doctor recommended home oxygen monitoring for patients with COVID-19 because they “believed that information about oxygen levels may help some people seek care earlier if their oxygen level begins to drop”.

Benefits of using a pulse oximeter

Checking oxygen levels at home is beneficial for those diagnosed with COVID-19 or with symptoms that are highly suggestive of infection.

Monitoring your oxygen levels can provide reassurance. If you notice your oxygen levels dropping, you can reach out for medical help.

“The key to taking care of yourself at home with COVID-19 is to carefully monitor your symptoms, especially coughing, wheezing, shortness of breath, and fever, and to inform your healthcare provider about any worsening symptoms. “Paying attention to how you’re feeling is your best guide,” Michael S. Lipnick, M.D., assistant professor of anesthesia and critical care at the University of California, San Francisco, says.

COVID-19 is a viral respiratory illness. Most cases of COVID-19 are relatively mild and can be treated at home. Its symptoms are fever, dry cough, and, sometimes, shortness of breath. These range from mild to severe, and the most serious cases can be fatal, particularly in people who are older or have underlying medical conditions.


References:

  1. https://www.webmd.com/asthma/guide/hypoxia-hypoxemia#2
  2. https://blogs.webmd.com/webmd-doctors/20200428/what-is-a-pulse-oximeter-and-can-it-help-against-covid19
  3. https://www.consumerreports.org/medical-symptoms/covid-19-pulse-oximeters-oxygen-levels-faq/

Myocarditis, Inflammation of the Heart Muscle

Penn State doctor says 30-35% of Big Ten athletes testing positive for COVID-19 had myocarditis symptoms.

Cardiac MRI scans revealed that roughly a third of all athletes who have tested positive for the coronavirus appear to have myocarditis, an inflammation of the heart muscle, said Penn State’s director of athletic medicine.

Myocarditis is an inflammation of the heart muscle that can lead to arrhythmia, cardiac arrest and death, especially in a person who doesn’t know they have it and performs rigorous exercise. The risk of myocarditis was a prime reason behind the Big Ten Conference’s decision to postpone the upcoming football season.

According to the Mayo Clinic, “In many cases, myocarditis improves on its own or with treatment, leading to a complete recovery.”

Even in mild cases of myocarditis, however, the clinic suggests that “persons should avoid competitive sports for at least three to six months.”

The cause of COVID-19 myocarditis is unclear. Some researchers speculate that the coronavirus may sometimes directly infect the heart.

Another possible culprit is the immune system’s response against the virus. When it fires out of control — a severe inflammatory reaction known as a cytokine storm — it can damage organs throughout the body, including the heart.


References:

  1. https://www.usatoday.com/story/sports/ncaaf/bigten/2020/09/03/big-ten-athletes-covid-had-myocarditis-symptoms-one-third-cases/5704234002/
  2. https://www.washingtonpost.com/sports/2020/09/03/big-ten-coronavirus-myocarditis/
  3. https://www.webmd.com/lung/news/20200415/covid-19-can-trigger-serious-heart-injuries

COVID-19 Frequently Asked Questions | New York Times

Updated September 1, 2020

  • Why is it safer to spend time together outside?
    • Pandemic life is safer outdoors. Outdoor gatherings lower risk because wind disperses viral droplets, and sunlight can kill some of the virus. Open spaces prevent the virus from building up in concentrated amounts and being inhaled, which can happen when infected people exhale in a confined space for long stretches of time, said Dr. Julian W. Tang, a virologist at the University of Leicester. Thus, while the risk of outdoor transmission is low, it can happen.
    • “The virus load is important,” said Eugene Chudnovsky, a physicist at Lehman College and the City University of New York’s Graduate Center. “A single virus will not make anyone sick; it will be immediately destroyed by the immune system. The belief is that one needs a few hundred to a few thousand of SARS-CoV-2 viruses to overwhelm the immune response.”

  • What are the symptoms of coronavirus?
    • In the beginning, the coronavirus seemed like it was primarily a respiratory illness — many patients had fever and chills, were weak and tired, and coughed a lot, though some people don’t show many symptoms at all. Those who seemed sickest had pneumonia or acute respiratory distress syndrome and received supplemental oxygen. By now, doctors have identified many more symptoms and syndromes. In April, the C.D.C. added to the list of early signs sore throat, fever, chills and muscle aches. Gastrointestinal upset, such as diarrhea and nausea, has also been observed. Another telltale sign of infection may be a sudden, profound diminution of one’s sense of smell and taste. Teenagers and young adults in some cases have developed painful red and purple lesions on their fingers and toes — nicknamed “Covid toe” — but few other serious symptoms.

    Why does standing six feet away from others help?

    • The coronavirus spreads primarily through droplets from your mouth and nose, especially when you cough or sneeze. The C.D.C., one of the organizations using that measure, bases its recommendation of six feet on the idea that most large droplets that people expel when they cough or sneeze will fall to the ground within six feet. But six feet has never been a magic number that guarantees complete protection. Sneezes, for instance, can launch droplets a lot farther than six feet, according to a recent study. It’s a rule of thumb: You should be safest standing six feet apart outside, especially when it’s windy. But keep a mask on at all times, even when you think you’re far enough apart.

    COVID-19 risk factors for severe disease

    • Based on currently available information and clinical expertise, older adults and people with underlying medical conditions are at higher risk for severe illness from COVID-19. According to the CDC, “…6% of the deaths, COVID-19 was the only cause mentioned.” Essentially, 94 percent of Americans who have died from coronavirus from the week ending February 1, 2020 to the week ending August 22, 2020 had, on average, almost three comorbidities that played a role in their death.
    • According to CDC’s report, the leading comorbidities among COVID-19 deaths were respiratory diseases, circulatory diseases, sepsis, malignant neoplasms, diabetes, obesity and Alzheimer’s disease, respectively.
    • “Anecdotally, there are several stories of cases in which people with COVID-19 had deadly heart attacks, yet these cases were coded as COVID-19 deaths. In one extreme case, a Florida man who died in a motorcycle crash happened to also have COVID-19 at the time, yet was coded as having died from COVID-19, not because of the motorcycle accident.” Many clinicians are putting COVID-19 on death certificates when it might not be entirely accurate because they died infected with coronavirus and not because of coronavirus.

    Sources:

    1. https://nyti.ms/31jGhk2
    2. https://www.cdc.gov/coronavirus/2019-ncov/faq.html